Infigratinib靶向的FGFR3（成纤维细胞生长因子受体3）正是驱动ACH疾病发生的关键靶点，2月12日，BridgeBio公布Infigratinib在ACH中取得的首个具有统计学显著改善意义的3期顶线结果，公司计划下半年向FDA提交新药申请。
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Like capitalism, looksmaxxing is all about optimization. The goal is to "ascend" — but why and to where, however, is unclear. Perhaps the goal is just to be on top, be the best, become rich, and have an attractive wife who "mogs" all your friends' wives. (As Mashable's Crystal Bell explained in December, mogging means outshining or overshadowing someone in appearance.)